Instituto de Microelectrónica de Barcelona

Welcome to the Biomedical Applications Group (GAB) web!

We are placed at the Barcelona Microelectronics Institute (IMB-CNM, CSIC) and we also belong to the CIBER-BBN. The GAB is a recognized and consolidated group by the Generalitat de Catalunya (SGR2014).

The  group takes advantage of the technological capacities available at the  Clean Room of the IMB-CNM in order to provide novel solutions to different biomedical applications. These solutions are mainly based on impedance sensing at different levels of biological organization, i.e. mollecules, cells and organs. As a consequence, the group works jointly with   different biomedical research groups, from the theoretical analysis to the  final clinical trials.


Unlocking the brain with novel graphene technology

Recent developments on a novel graphene-based sensing platform, which provides high resolution, real-time measuring of brain activity, could be the gateway to unlocking a superior understanding of the brain. This research, developed in the framework of the EU project BrainCom and participated by the Biomedical Applications Group of the IMB-CNM, is reported in four papers recently published on high impact journals.

Arguably, a better understanding of the working principles of the human brain remains one of the major scientific challenges of our time. Despite significant advances made in the field of neurotechnology in recent years, neural sensing interfaces still fall short of equally meeting requirements on biocompatibility, sensitivity, and high spatio-temporal resolution. The European Union Horizon 2020 research project BrainCom, coordinated by the ICN2 Advanced Electronic Materials and Devices Group led by ICREA Prof. José A. Garrido, is tackling these problems. BrainCom brings together experts from the fields of neurotechnology, neuroscience, and ethics to develop novel technologies capable of overcoming these limitations and shed light onto the mechanisms of information encoding and processing in the brain.

New microsensor for characterizing biofilms

A biofilm can be defined in many ways, but in short we could say that it is a heterogeneous and very complex morphological and chemical accumulation of salts, organic matter and microorganisms, among others, that grow on a surface. There are unwanted biofilms that we strive to fight daily, as is the case with dental plaque. Other well-known and undesirable examples are those biofilms that grow on the inside walls of a drain.

In the field of waste treatment, microorganisms are used to remove undesirable compounds from wastewater or contaminated gas streams. In this case, however, the growth of these biofilm cultures in bioreactors is a very interesting alternative for efficient, robust and compact treatment systems. For the good design and operation of these bioreactors it is necessary to understand what these biofilms are, how they are formed and how they evolve. These biofilms are often less than a few millimeters thick, even less than a few hundred microns in size, making microsensors very interesting tools for studying and characterizing these biological systems. Extremely fragile and expensive commercial glass microsensors are generally used to measure a single compound at a single point in the biofilm. With the help of a micromanipulator, profiles of that compound can be measured inside the biofilms.

Sede: Campus UAB. Cerdanyola del Vallès. Barcelona. E-08193 (Españ
Tel:(+34) 93 594 7700 Fax:(+34) 93 580 1496