CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS
Instituto de Microelectrónica de Barcelona

Welcome to the Biomedical Applications Group (GAB) web!

We are placed at the Barcelona Microelectronics Institute (IMB-CNM, CSIC) and we also belong to the CIBER-BBN. The GAB is a recognized and consolidated group by the Generalitat de Catalunya (SGR2014).

The  group takes advantage of the technological capacities available at the  Clean Room of the IMB-CNM in order to provide novel solutions to different biomedical applications. These solutions are mainly based on impedance sensing at different levels of biological organization, i.e. mollecules, cells and organs. As a consequence, the group works jointly with   different biomedical research groups, from the theoretical analysis to the  final clinical trials.
 

News

Scientists emulate the human blood–retinal barrier on a microfluidic chip

The device contains living cells and mimics the structure and physiological conditions of the blood–retinal barrier. It can be use for testing molecules in vitro and studying diseases such as diabetic retinopathy. It has been developed by scientists at the Barcelona Microelectronics Institute (IMB-CNM) of the CSIC, the CIBER-BBN centre, and at the UAB; together with scientists at the Diabetes and Metabolism group of the Vall d’Hebron Research Institute (VHIR) and CIBERDEM- Institute of Health Carlos III.

For some years, scientists have been researching in order to find ways of reducing animal testing and accelerating clinical trials. In vitro assays with living cells is an alternative, but it has limitations as the interconnection and interaction between cells cannot be easily reproduced.

To overcome the latest, scientists are developing systems that mimic tissues and organ functions in conditions very close to reality. These types of devices, called “Organ-on-a-chip”, include microenvironments and microarchitectures in order to emulate the living organs and tissues.

Read more...
 
El Liver on a Chip guardonat com una de les Millors Idees del 2016 pel Diario Médico

La festa de les Millors Idees de l’Any en matèria sanitària, impulsada per Diario Médico i que va tenir lloc al Teatre Nacional de Catalunya el dilluns 28 de novembre va guardonar el projecte Liver on a Chip desenvolupat pel GAB juntament amb el Laboratori d’Hemodinàmica Hepàtica de l’IDIBAPS. El projecte es basa en el treball realitzant durant aquests últims anys pels dos grups per tal de dissenyar i fabricar una cambra de co-cultiu cel·lular que simula el microambient de l’interior del fetge.

El premi fou recollit per tres dels membres del GAB, Rosa Villa, Xavi Illa i Martí Ortega

 
 
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