This research line aims to develop innovative chemical and technological strategies to enhance the sensing capabilities of emerging biosensors. Given the expertise in functionalization and the technological resources of the group, the team is advancing in new chemical approaches for multiple detection systems based on graphene solution-gated field-effect transistors (gSGFETs). By enabling the simultaneous sensing of different analytes, this research will significantly contribute to the multiomics field, facilitating the collection of extensive data crucial for personalized medicine. Currently, the group is working on modifying surfaces with bifunctional spacers that can functionalize specific areas and the upscaling of this approach at wafer level.
In partnership with other groups from clinical domains, this research aims to exploit the unique properties of gSGFETs for real-time monitoring in different biomedical applications. Moreover, we are exploring the combination of sensing and recording capabilities of gSGFETs for studying multimodal neural biomarkers by integrating an interstitial ion concentration sensing sites.
Related publications:
Brosel-Oliu S, Rius G, Aviñó A, Nakatsuka N, Illa X, del Corro E, Delgà-Fernández M, Masvidal-Codina E, Rodríguez N, Merino JP, Criado A, Prato M, Tkatchenko R, Eritja R, Godignon P, Garrido JA, Villa R, Guimerà A, Prats-Alfonso E. Single-Step Functionalization Strategy of Graphene Microtransistor Array with Chemically Modified Aptamers for Biosensing Application. Small (2023) 2308857. https://doi.org/10.1002/smll.202308857
Contact: Elisabet Prats